| dc.contributor.author | Bera, Smritilekha | |
| dc.contributor.author | Linhardt, Robert J. | |
| dc.date | 2011 | |
| dc.date.accessioned | 2022-06-27T16:08:47Z | |
| dc.date.available | 2022-06-27T16:08:47Z | |
| dc.date.issued | 2011-05-06 | |
| dc.identifier.citation | Design and synthesis of unnatural heparosan and chondroitin building blocks, S. Bera, R. J. Linhardt, Journal of Organic Chemistry, 76, 3181-3189, 2011. | |
| dc.identifier.issn | 15206904 | |
| dc.identifier.issn | 223263 | |
| dc.identifier.uri | https://doi.org/10.1021/jo200076z | |
| dc.identifier.uri | https://hdl.handle.net/20.500.13015/5727 | |
| dc.description | Journal of Organic Chemistry, 76, 3181-3189 | |
| dc.description | Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform. | |
| dc.description.abstract | Triazole linked heparosan and chondroitin disaccharide and tetrasaccharide building blocks were synthesized in a stereoselective manner by applying a very efficient copper catalyzed azide−alkyne cycloaddition (CuAAC) reaction of appropriately substituted azido-glucuronic acid and propargyluted N-acetyl glucosamine and N-acetyl galactosamine derivative, respectively. The resulting suitably substituted tetrasaccharide analogues can be easily converted into azide and alkyne unit for further synthesis of higher oligosaccharide analogues. | |
| dc.description.sponsorship | National Heart, Lung, and Blood Institute | |
| dc.description.uri | https://login.libproxy.rpi.edu/login?url=https://doi.org/10.1021/jo200076z | |
| dc.language | en_US | |
| dc.language.iso | ENG | |
| dc.relation.ispartof | The Linhardt Research Labs Online Collection | |
| dc.relation.ispartof | Rensselaer Polytechnic Institute, Troy, NY | |
| dc.relation.ispartof | Journal of Organic Chemistry | |
| dc.relation.uri | https://harc.rpi.edu/ | |
| dc.subject | Biology | |
| dc.subject | Chemistry and chemical biology | |
| dc.subject | Chemical and biological engineering | |
| dc.subject | Biomedical engineering | |
| dc.title | Design and synthesis of unnatural heparosan and chondroitin building blocks | |
| dc.type | Article | |
| dcterms.accessRights | https://login.libproxy.rpi.edu/login?url=https://doi.org/10.1021/jo200076z | |
| dcterms.isPartOf | Journal | |
| dcterms.isVersionOf | https://doi.org/10.1021/jo200076z | |
| dc.rights.holder | In Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/ | |
| dc.creator.identifier | https://orcid.org/0000-0003-2219-5833 | |
| dc.relation.department | The Linhardt Research Labs. | |
| dc.relation.department | The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS) | |
| rpi.description.pages | 3181-3193 | |
| rpi.description.volume | 76 | |
