Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
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E. coli K5 heparosan fermentation and improvement by genetic engineering, Z. Wang, J. S. Dordick, R. J. Linhardt, Bioengineered Bugs, 2, 1-15, 2011.
N-acetyl heparosan is the precursor for the biosynthesis of the important anticoagulant drug heparin. The E. coli K5 capsular heparosan polysaccharide provides a promising precursor for in vitro chemoenzymatic production of bioengineered heparin. This article explores the improvements of heparosan production for bioengineered heparin by fermentation process engineering and genetic engineering.;
Bioengineered Bugs, 2, 1-15; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; https://harc.rpi.edu/;