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E. coli K5 heparosan fermentation and improvement by genetic engineering

dc.contributor.authorWang, Z.
dc.contributor.authorDordick, J.S.
dc.contributor.authorLinhardt, Robert J.
dc.date2011
dc.date.accessioned2022-06-27T16:08:47Z
dc.date.available2022-06-27T16:08:47Z
dc.date.issued2011
dc.identifier.citationE. coli K5 heparosan fermentation and improvement by genetic engineering, Z. Wang, J. S. Dordick, R. J. Linhardt, Bioengineered Bugs, 2, 1-15, 2011.
dc.identifier.urihttps://doi.org/10.4161/bbug.2.1.14201
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5731
dc.descriptionBioengineered Bugs, 2, 1-15
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractN-acetyl heparosan is the precursor for the biosynthesis of the important anticoagulant drug heparin. The E. coli K5 capsular heparosan polysaccharide provides a promising precursor for in vitro chemoenzymatic production of bioengineered heparin. This article explores the improvements of heparosan production for bioengineered heparin by fermentation process engineering and genetic engineering.
dc.languageen_US
dc.language.isoENG
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleE. coli K5 heparosan fermentation and improvement by genetic engineering
dc.typeArticle
dcterms.isVersionOfhttps://doi.org/10.4161/bbug.2.1.14201
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)


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