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dc.contributor.authorPark, Youmie
dc.contributor.authorIm, A. Rang
dc.contributor.authorJoo, Eun Ji
dc.contributor.authorLee, Jihye
dc.contributor.authorPark, Hyeung Geun
dc.contributor.authorKang, Young Hwa
dc.contributor.authorLinhardt, Robert J.
dc.contributor.authorKim, Yeong Shik
dc.identifier.citationConjugation of ginsenoside Rg3 with gold nanoparticles, Y. Park, A.-R. Im, E. J. Joo, J. Lee, H.-G. Park, R. J. Linhardt, Y. S. Kim, Bulletin of the Korean Chemical Society, 32, 286-290, 2011.
dc.descriptionBulletin of the Korean Chemical Society, 32, 286-290
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractGinsenoside Rg3 was reported to have important biological activities. We demonstrate conjugation and quantification procedures of ginsenoside Rg3 to gold nanoparticles for future biological and medical applications. Ginsenoside Rg3 was conjugated to spherical gold nanoparticles using a bifunctional heptaethylene glycol linker. The sulfhydryl group of heptaethylene glycol was adsorbed onto gold nanoparticles, and carboxylic acid end of heptaethylene glycol was bonded through a hydroxyl group of Rg3 via ester bond formation. The conjugation of Rg3 was characterized with various spectroscopic techniques, high resolution-transmission electron microscopy, and using Rg3 monoclonal antibody. These results suggest that ginsenoside Rg3 is successfully conjugated to gold nanoparticles via heptaethylene glycol linker. The quantification was performed by using Rg3 monoclonal antibody without interference of gold's intrinsic color.
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofBulletin of the Korean Chemical Society
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleConjugation of ginsenoside Rg3 with gold nanoparticles
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)

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