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dc.contributor.authorLy, Mellisa
dc.contributor.authorLaremore, Tatiana N.
dc.contributor.authorLinhardt, Robert J.
dc.date2010
dc.date.accessioned2022-06-27T16:10:54Z
dc.date.available2022-06-27T16:10:54Z
dc.date.issued2010-08-01
dc.identifier.citationProteoglycomics: Recent progress and future challenges, M. Ly, T. N. Laremore, R. J. Linhardt, Omics, 14, 389-399, 2010.
dc.identifier.issn15362310
dc.identifier.urihttps://doi.org/10.1089/omi.2009.0123
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5737
dc.descriptionOmics, 14, 389-399
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractProteoglycomics is a systematic study of structure, expression, and function of proteoglycans, a posttranslationally modified subset of a proteome. Although relying on the established technologies of proteomics and glycomics, proteoglycomics research requires unique approaches for elucidating structure-function relationships of both proteoglycan components, glycosaminoglycan chain, and core protein. This review discusses our current understanding of structure and function of proteoglycans, major players in the development, normal physiology, and disease. A brief outline of the proteoglycomic sample preparation and analysis is provided along with examples of several recent proteoglycomic studies. Unique challenges in the characterization of glycosaminoglycan component of proteoglycans are discussed, with emphasis on the many analytical tools used and the types of information they provide.
dc.description.sponsorshipNational Heart, Lung, and Blood Institute
dc.description.urihttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1089/omi.2009.0123
dc.languageen_US
dc.language.isoENG
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofOMICS A Journal of Integrative Biology
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleProteoglycomics: Recent progress and future challenges
dc.typeArticle
dcterms.accessRightshttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1089/omi.2009.0123
dcterms.isPartOfJournal
dcterms.isVersionOfhttps://doi.org/10.1089/omi.2009.0123
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages389-399
rpi.description.volume14


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