Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
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Thin Layer Chromatography for the Separation and Analysis of Acidic Carbohydrates, Z. Zhang, Z. Xiao, R.J. Linhardt, Journal of Liquid Chromatography & Related Technologies, 32, 1711–1732, 2009.
Thin layer chromatography (TLC) is routinely used by synthetic organic chemists and natural products chemists working on a variety of types of molecules. Carbohydrate chemists and biochemists in the past largely relied on paper chromatography for rapid and inexpensive analysis. Carbohydrates are highly polar molecules and often require derivatization to be analyzed by TLC. Acidic carbohydrates pose an even more difficult challenge as they contain a formal negative charge and counterion, and can interact with commonly used stationary phases. This review describes TLC methods that have been developed for the analysis of acidic monosaccharides, disaccharides, and oligosaccharides derived from natural sources.;
Journal of Liquid Chromatography & Related Technologies, 32, 1711–1732; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; Journal of Liquid Chromatography and Related Technologies; https://harc.rpi.edu/;