Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
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Previews: Heparin-Induced Cancer Cell Death, R. J. Linhardt, Chemistry & Biology, 11, 420-422, 2004.
Heparin uptake into cancer cells can be promoted by conjugation to poly (β-amino ester)s. Internalized heparin is cytotoxic, causing cancer cell death by interfering with transcription factor activity and inducing apoptosis, but only certain poly(β-amino ester)s promote this activity.;
Chemistry & Biology, 11, 420-422; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; https://harc.rpi.edu/;