Author
Linhardt, Robert J.
Other Contributors
Date Issued
2004
Subject
Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
Degree
Terms of Use
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Full Citation
Previews: Heparin-Induced Cancer Cell Death, R. J. Linhardt, Chemistry & Biology, 11, 420-422, 2004.
Abstract
Heparin uptake into cancer cells can be promoted by conjugation to poly (β-amino ester)s. Internalized heparin is cytotoxic, causing cancer cell death by interfering with transcription factor activity and inducing apoptosis, but only certain poly(β-amino ester)s promote this activity.;
Description
Chemistry & Biology, 11, 420-422; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Department
The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
Relationships
The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; https://harc.rpi.edu/;
Access
https://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.chembiol.2004.04.001;