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dc.contributor.authorDu, Y.
dc.contributor.authorPolat, T.
dc.contributor.authorLinhardt, Robert J.
dc.date1998
dc.date.accessioned2022-06-27T16:21:52Z
dc.date.available2022-06-27T16:21:52Z
dc.date.issued1998
dc.identifier.citationThe Stereospecific Synthesis of KDN a-C-glycosides by Samarium-Mediated Reductive Desulfonylation ofGlycosyl Phenylsulfone, Y. Du, T. Polat, R.J. Linhardt, TetrahedronLetters, 39, 5007-5010, 1998.
dc.identifier.urihttps://doi.org/10.1016/S0040-4039(98)00980-0
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5896
dc.descriptionTetrahedron Letters, 39, 5007-5010
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractKDN, 3-deoxy-D-glycero-D-galacto-2-nonulopyranosylonic acid, is a novel type of sialic acid in which the acetamido group at C-S of N-acetylneuraminic acid is replaced by a hydroxyl group. This ulosonic acid was first isolated from rainbow trout eggs.’ In the last 10 years, a number of KDN-glycoconjugates, exhibiting structural determinants related to human tumor-associated antigens, have been reported in mammals2 In addition, oligo/poly-KDN and KDN-glycoprotein play an important role in the binding of calcium ions.’ KDN-containing gangliosides, KDN-GM3 and KDN-GM4, have been synthesized by Hasegawa’s group and show potent inhibitor activity of cellular immune respones.
dc.description.urihttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/S0040-4039(98)00980-0
dc.languageen_US
dc.language.isoENG
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleThe Stereospecific Synthesis of KDN a-C-glycosides by Samarium-Mediated Reductive Desulfonylation ofGlycosyl Phenylsulfone
dc.typeArticle
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dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)


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