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dc.contributor.authorFromm, J.R.
dc.contributor.authorHileman, R.E.
dc.contributor.authorWeiler, J.M.
dc.contributor.authorLinhardt, Robert J.
dc.date1997
dc.date.accessioned2022-06-27T16:22:19Z
dc.date.available2022-06-27T16:22:19Z
dc.date.issued1997
dc.identifier.citationInteraction of Fibroblast Growth Factor-1 and Related Peptideswith Heparan Sulfate and Its Oligosaccharides, J. R. Fromm, R. E. Hileman,J. M. Weiler, R.J. Linhardt, Archives in Biochemistry and Biophysics,346,252-262, 1997.
dc.identifier.urihttps://doi.org/10.1006/abbi.1997.0299
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5911
dc.descriptionArchives in Biochemistry and Biophysics, 346, 252-262
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractFibroblast growth factors (FGFs) are a family of an-with the highest affinity to heparan sulfate. These datagiogenic and mitogenic proteins that promote cell divi-suggest the triangular topology of the GAG bindingsion. The binding of FGFs to the heparan sulfate ofsite in FGF is critical for its interaction with heparancell-surface-bound proteoglycans appears to be criti-sulfate. Analysis of known GAG binding sites in 25 pro-cal for their activity. The interaction of fibroblastteins using the Chou – Fasman algorithm show thatgrowth factor-1 (FGF-1 or aFGF) using heparin lyase-these sites commonly contain turns.q1997 Academic Pressderived oligosaccharides from heparan sulfate was in-vestigated.
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dc.languageen_US
dc.language.isoENG
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleInteraction of Fibroblast Growth Factor-1 and Related Peptideswith Heparan Sulfate and Its Oligosaccharides
dc.typeArticle
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dcterms.isVersionOfhttps://doi.org/10.1006/abbi.1997.0299
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dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)


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