Synthesis of the Bis-Tetrahydropyrano[2,3-b:2’,3’-e] Piperazine Ring System: A New Tricyclic Heterocycle from D-Glucosamine

Authors
Kerns, Robert J.
Toida, Toshihiko
Linhardt, Robert J.
ORCID
https://orcid.org/0000-0003-2219-5833
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Other Contributors
Issue Date
1996-01-01
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Degree
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Full Citation
Synthesis of the Bis-Tetrahydropyrano[2,3-b:2’,3’-e] Piperazine Ring System: A New Tricyclic Heterocycle from D-Glucosamine, R.J. Kerns, T. E. Toida, R.J. Linhardt, Journal of Carbohydrate Chemistry, 15, 581-590, 1996.
Abstract
2-Amino-3,4,6-tri-O-benzyl-2-deoxy-D-glucopyranose was transformed into its bis(tetrahydropyranyl)piperazine dimer (4) by reaction with 1,1′-thionyldiimidazole or 1,1′-sulfonyldiimidazole. This dimeric form of glucosamine is the first representative of this previously unknown heterocyclic ring system.
Description
Journal of Carbohydrate Chemistry, 15, 581-590
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Department
The Linhardt Research Labs.
The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
Publisher
Relationships
The Linhardt Research Labs Online Collection
Rensselaer Polytechnic Institute, Troy, NY
Journal of Carbohydrate Chemistry
https://harc.rpi.edu/
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