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dc.contributor.authorDesai, Umesh R.
dc.contributor.authorVlahov, Ioncho R.
dc.contributor.authorPervin, Azra
dc.contributor.authorLinhardt, Robert J.
dc.date1995
dc.date.accessioned2022-06-27T17:13:46Z
dc.date.available2022-06-27T17:13:46Z
dc.date.issued1995-10-02
dc.identifier.citationConformational Analysis of Sucrose Octasulfate by High Resolution Nuclear Magnetic Resonance Spectroscopy, U.R. Desai, I. R. Vlahov, A. Pervin, R. J. Linhardt, Carbohydrate Research, 275, 391-401, 1995.
dc.identifier.issn86215
dc.identifier.urihttps://doi.org/10.1016/0008-6215(95)00159-Q
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5946
dc.descriptionCarbohydrate Research, 275, 391-401
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractThe aluminum salt of sucrose octasulfate (SOS) is a drug called Sucralfate (Carafate), which is widely used for the treatment of duodenal ulcers. Folkman et al. [1] have recently suggested that Sucralfate binds to fibroblast growth factor (FGF), protecting it from denaturation in the strongly acidic conditions present in the stomach. This hypothesis has generated considerable interest in sucrose octasulfate and its interaction with FGF. The sodium and potassium salts of SOS also bind FGF [2], but these differ from Sucralfate in being water soluble and are more easily studied.
dc.description.sponsorshipNational Institute of General Medical Sciences
dc.description.urihttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/0008-6215(95)00159-Q
dc.languageen_US
dc.language.isoENG
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofCarbohydrate Research
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleConformational Analysis of Sucrose Octasulfate by High Resolution Nuclear Magnetic Resonance Spectroscopy
dc.typeArticle
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dcterms.isVersionOfhttps://doi.org/10.1016/0008-6215(95)00159-Q
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages391-401
rpi.description.volume275


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