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dc.contributor.authorLinhardt, Robert J.
dc.contributor.authorHileman, Ronald E.
dc.date1995
dc.date.accessioned2022-06-27T17:14:13Z
dc.date.available2022-06-27T17:14:13Z
dc.date.issued1995-01-01
dc.identifier.citationDermatan Sulfate as a Potential Therapeutic Agent, R. J. Linhardt, R. E. Hileman, General Pharmacology, 26, 443-451, 1995.
dc.identifier.issn3063623
dc.identifier.urihttps://doi.org/10.1016/0306-3623(94)00231-B
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5954
dc.descriptionGeneral Pharmacology, 26, 443-451
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractDermatan sulfate is a linear, sulfated polysaccharide and is a glycosaminoglycan component of several important proteoglycans. This minireview discusses the biosynthesis, structure and biological function of dermatan sulfate proteoglycans. 2. Dermatan sulfate and its derivatives are being investigated as a new class of anticoagulant and antithrombotic agents. 3. The preparation, chemistry and structure-activity relationship of dermatan sulfate is described. 4. Dermatan sulfate, low molecular weight dermatan sulfate and glycosaminoglycan mixtures containing dermatan sulfate have been used clinically. 5. The future prospects of these agents and other new, potentially useful dermatan sulfate based therapeutics are discussed.
dc.description.sponsorshipNational Institute of General Medical Sciences
dc.description.urihttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/0306-3623(94)00231-B
dc.languageen_US
dc.language.isoENG
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofGeneral Pharmacology
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleDermatan Sulfate as a Potential Therapeutic Agent
dc.typeArticle
dcterms.accessRightshttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/0306-3623(94)00231-B
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dcterms.isVersionOfhttps://doi.org/10.1016/0306-3623(94)00231-B
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages443-451
rpi.description.volume26


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