Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
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Biodegradable Polymers for the Controlled Delivery of Vaccines, E. Schmitt, D.R. Flanagan, R.J. Linhardt, Proceedings of the ACS Division of Polymeric Materials: Science and Engineering, 66, 493-494 (1992).
New methods for the efficient and effective administration of vaccines are required particularly with the advent of new synthetic subunit vaccines. This chapter describes the approaches of several research groups to administer vaccines using biodegradable polymer carriers. Delivery systems composed of synthetic poly[esters] and poly[iminocarbonates] and natural (crosslinked serum albumin) biodegradable polymers are described. The antibody levels in response to these systems are presented, and possible mechanisms responsible for the observed effects are discussed. The important questions that need to be answered before this technology can be successfully applied are also discussed.;
Proceedings of the ACS Division of Polymeric Materials: Science and Engineering, 66, 493-494; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; https://harc.rpi.edu/;