Synthesis, structural, and biological studies on a pseudodisaccharide containing a bicyclic, bridged carba-sugar
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Authors
Fejes, Zsolt
Kurtán, Tibor
Raabe, Gerhard
Fleischhauer, Jörg
Szilágyi, László
Bényei, Attila
Gál, Zoltán
Zhao, Wenjing
Linhardt, Robert J.
Cygler, Miroslaw
Issue Date
2011-07-15
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Alternative Title
Abstract
Two carba-sugar containing pseudodisaccharide diastereomers have been synthesized from a racemic bicyclooctene derivative. The determination of the absolute configurations was carried out by means of CD measurements, CD calculations and X-ray diffraction. The compounds showed moderate competitive inhibitory effects on chondroitin AC-I lyase.
Description
Tetrahedron: Asymmetry, 22, 1404-1410
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Synthesis, structural, and biological studies on a pseudodisaccharide containing a bicyclic, bridged carba-sugar, Z. Fejes, T. Kurtán, G. Raabe, J. Fleischhauer, L. Szilágyi, A. Bényei, Z. Gál, W. Zhao, R. J. Linhardt, M. Cygler, P. Herczegh, Tetrahedron: Asymmetry, 22, 1404-1410, 2011.
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Journal
Volume
Issue
PubMed ID
DOI
ISSN
1362511X
9574166
9574166