Synthesis, structural, and biological studies on a pseudodisaccharide containing a bicyclic, bridged carba-sugar

Authors
Fejes, Zsolt
Kurtán, Tibor
Raabe, Gerhard
Fleischhauer, Jörg
Szilágyi, László
Bényei, Attila
Gál, Zoltán
Zhao, Wenjing
Linhardt, Robert J.
Cygler, Miroslaw
ORCID
https://orcid.org/0000-0003-2219-5833
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Other Contributors
Issue Date
2011-07-15
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Degree
Terms of Use
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Full Citation
Synthesis, structural, and biological studies on a pseudodisaccharide containing a bicyclic, bridged carba-sugar, Z. Fejes, T. Kurtán, G. Raabe, J. Fleischhauer, L. Szilágyi, A. Bényei, Z. Gál, W. Zhao, R. J. Linhardt, M. Cygler, P. Herczegh, Tetrahedron: Asymmetry, 22, 1404-1410, 2011.
Abstract
Two carba-sugar containing pseudodisaccharide diastereomers have been synthesized from a racemic bicyclooctene derivative. The determination of the absolute configurations was carried out by means of CD measurements, CD calculations and X-ray diffraction. The compounds showed moderate competitive inhibitory effects on chondroitin AC-I lyase.
Description
Tetrahedron: Asymmetry, 22, 1404-1410
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Department
The Linhardt Research Labs.
The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
Publisher
Relationships
The Linhardt Research Labs Online Collection
Rensselaer Polytechnic Institute, Troy, NY
Tetrahedron Asymmetry
https://harc.rpi.edu/
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