Rational design and high-throughput screening of peptide affinity ligands
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Authors
Chandra, Divya
Issue Date
2013-12
Type
Electronic thesis
Thesis
Thesis
Language
ENG
Keywords
Chemical engineering
Alternative Title
Abstract
Finally, from a fundamental standpoint, we find that screening a few hundred protein-peptide interactions is not only advantageous for affinity ligand design, but can also provide significant preliminary insights for elucidating large-scale protein-protein interactions and complex formation. We have demonstrated this for the cTn complex as well as for hTf and its receptors.
Description
December 2013
School of Engineering
School of Engineering
Full Citation
Publisher
Rensselaer Polytechnic Institute, Troy, NY