Draft Genome Sequence of Escherichia coli Strain ATCC #23502 (1 Serovar O5:K4(L):H4)

Cress, B.F.
Greene, Z.R.
Linhardt, Robert J.
Koffas, M.A.G.
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Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
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Draft Genome Sequence of Escherichia coli Strain ATCC #23502 (1 Serovar O5:K4(L):H4), B. F. Cress, Z. R. Greene, R. J. Linhardt, M.A.G. Koffas, Genome Announcements, 1, e00046-13, 2013.
We report the 4.682-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23502 (serovar O5:K4:H4, also known as NCDC U1-41) genome. This uropathogenic strain, commonly referred to as E. coli K4, produces a glycosaminoglycan-like capsular polysaccharide with a backbone similar in structure to unsulfated chondroitin, a precursor to the nutraceutically and potentially pharmaceutically valuable compound chondroitin sulfate. Metabolic reconstruction of this genome will enable prediction of genetic engineering strategies leading to increased chondroitin production.
Genome Announcements, 1, e00046-13
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The Linhardt Research Labs.
The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
The American Society for Microbiology (ASM)
The Linhardt Research Labs Online Collection
Rensselaer Polytechnic Institute, Troy, NY
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