Design and implementation of the web interfaces and middleware for synergy project

Zhuang, Juntao
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Szymanśki, Bolesław
Krishnamoorthy, M. S.
Yener, Bülent, 1959-
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Computer science
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Attribution-NonCommercial-NoDerivs 3.0 United States
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
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Recent biomedical researches usually involve novel combination of molecules. The goal of the Synergy Project is to facilitate biomedical researchers to find hidden relation among molecules and their potential collaborators. By gathering the data of publications from researchers, information such as authors, molecules, research papers title etc. are stored layer-by-layer in our multi-layer graph network. For each search focusing on a small set of molecules, the scientists whose research is most related to these molecules are listed by our algorithms after processing information within and across the network layers.
In this M.S thesis, we create a website for scientists to enter the list of molecules they are researching on. We also implement a middleware connecting this website with frontend interface and backend graph database. Another contribution of this thesis is a caching and queueing system implemented for concurrent query. For further increase of access, the middleware is scalable across multiple machines.
May 2017
School of Science
Dept. of Computer Science
Rensselaer Polytechnic Institute, Troy, NY
Rensselaer Theses and Dissertations Online Collection
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