Effect of load frequency on trans-endplate transport of nutrients to the intervertebral disc

Authors
Shah, Mitul A.
ORCID
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Other Contributors
Hahn, Juergen
Ledet, Eric H.
Hahn, Juergen
Ledet, Eric H.
Wan, Leo Q.
Zhang, Lucy T.
Issue Date
2015-05
Keywords
Biomedical engineering
Degree
PhD
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
Abstract
The model shows that the total nutrient transport to the disc can be augmented by a dynamic load. For healthy and degenerated discs, the maximum total nutrient transport is observed when the loading frequency of the applied mechanical load is approximately 0.5 Hz. As the frequency of loading increased past 0.5 Hz, tissue stiffening limits the total nutrient transport to the disc.
Description
May 2015
School of Engineering
Department
Dept. of Biomedical Engineering
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
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