Pathway optimization and balancing for the improved microbial production of high-value chemicals

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Authors
Jones, John Andrew
Issue Date
2016-05
Type
Electronic thesis
Thesis
Language
ENG
Keywords
Chemical engineering
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Abstract
Moving forward, the work contained here lays a solid framework for the optimization of chemical production pathways in E. coli. The techniques presented below, both genetic and fermentation-based, highlight the methods available to probe the sensitivity of microbial systems allowing for more in-depth analysis to be undertaken. It is clear that efforts in pathway optimization and balancing will be key to the smooth transition of microbially based chemical production platforms from the laboratory to the marketplace.
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May 2016
School of Engineering
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Rensselaer Polytechnic Institute, Troy, NY
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