Investigation and enhancement of lateral integration of tissue engineered articular cartilage under dynamic mechanical stimulation
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Authors
Mintz, Benjamin Ross
Issue Date
2014-12
Type
Electronic thesis
Thesis
Thesis
Language
ENG
Keywords
Biomedical engineering
Alternative Title
Abstract
Scaffolds were characterized as having little innate impact on chondrocyte phenotype, and exhibited little to no degradation after 6 weeks of culture. Optimization of the mechanical properties of the hybrid scaffolding material was performed by direct comparison with arthritic human articular cartilage tissue. Reformulated scaffolds possessed a high mean porosity of ~80% and a Poisson's ratio of 0.34.
Description
December 2014
School of Engineering
School of Engineering
Full Citation
Publisher
Rensselaer Polytechnic Institute, Troy, NY