Investigation and enhancement of lateral integration of tissue engineered articular cartilage under dynamic mechanical stimulation

Authors
Mintz, Benjamin Ross
ORCID
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Other Contributors
Cooper, James A.
Corr, David T.
Plopper, George E.
Ryu, Chang Yeol
Issue Date
2014-12
Keywords
Biomedical engineering
Degree
PhD
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
Abstract
Scaffolds were characterized as having little innate impact on chondrocyte phenotype, and exhibited little to no degradation after 6 weeks of culture. Optimization of the mechanical properties of the hybrid scaffolding material was performed by direct comparison with arthritic human articular cartilage tissue. Reformulated scaffolds possessed a high mean porosity of ~80% and a Poisson's ratio of 0.34.
Description
December 2014
School of Engineering
Department
Dept. of Biomedical Engineering
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
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