Heparinoids: Structure, Biological Activities and Therapeutic Applications
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Authors
Gunay, Nur Sibel
Linhardt, Robert J.
Issue Date
1999-06-08
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Alternative Title
Abstract
Heparin is an important polyanionic drug having a wide variety of different biological activities. Substantial research effort has focused on the preparation of improved heparins and heparin analogues that might exhibit higher specificity and decreased side effects. These heparin analogues or heparinoids include sulfated polysaccharides from plant and animal origin, synthetic derivatives of polysaccharides, and acidic oligosaccharides and their small synthetic analogues. The structure, biological activities and therapeutic potential of these heparinoids are discussed.
Description
Planta Medica, 65, 01-306
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Heparinoids: Structure, Biological Activities and TherapeuticApplications, N. S. Gunay, R.J. Linhardt, Planta Medica, 65,301-306, 1999.
Publisher
Terms of Use
Journal
Volume
Issue
PubMed ID
DOI
ISSN
320943