Peptidoglycan-targeting lytic enzymes for antimicrobial applications

Abstract

Taking advantage of the superior properties of peptidoglycan-targeting lytic enzymes, we have explored their applications in three different systems: Gram-positive bacterial spores, Gram-positive bacterial cells, and Gram-negative bacterial cells. We have investigated the detailed mechanisms of the lytic enzymes and their interactions with the target peptidoglycan in these systems.