Draft Genome Sequence of Escherichia coli Strain Nissle 1917 1 (Serovar O6:K5:H1)
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ORCID
https://orcid.org/0000-0003-2219-5833
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Article
Language
ENG
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Abstract
We announce the availability of the 5.023-Mbp high-quality draft assembly of the Escherichia coli strain Nissle 1917 (serovar O6:K5:H1) genome. Short genomic segments from this important probiotic strain have been available in public databases, but the full genome sequence has remained inaccessible. Thus, high-coverage, whole genome sequencing of E. coli Nissle 1917 is presented herein. Reannotation and metabolic reconstruction will enable comparative genomics analysis and model-guided predictions of genetic manipulations leading to increased production of the K5 capsular polysaccharide known as N-acetyl heparosan, a precursor to the anticoagulant pharmaceutical heparin.
Description
Genome Announcements, 1, e00047-13
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Draft Genome Sequence of Escherichia coli Strain Nissle 1917 1 (Serovar O6:K5:H1), B. F. Cress, R. J. Linhardt, M.A.G. Koffas, Genome Announcements, 1, e00047-13, 2013.
Publisher
The American Society for Microbiology (ASM)
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Attribution 3.0 United States