Synthesis of Sulfosucrose Derivatives for Evaluation as Regulators of Fibroblast Growth Factor Activity

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Authors
Polat, T.
Mohammadi, Moosa
Linhardt, Robert J.
Issue Date
2002-11-04
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
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Abstract
Based on X-ray crystallographic studies on sucrose octasulfate in complex with fibroblast growth factor and its receptor, three analogs of sucrose octasulfate were regioselectively synthesized for biological evaluation as regulations of cell proliferation and differentiation.
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Tetrahedron Letters, 43, 8047-8049
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Full Citation
Synthesis of Sulfosucrose Derivatives for Evaluation as Regulators of Fibroblast Growth Factor Activity, T. Polat, M. Mohammadi, R.J. Linhardt, Tetrahedron Letters, 43, 8047-8049, 2002.
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ISSN
404039
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