A study of biomolecules as growth modifiers of calcium oxalate crystals

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Authors
Kwak, Junha (John)
Issue Date
2017-05
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Electronic thesis
Thesis
Language
ENG
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Chemical engineering
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Abstract
Crystallization processes are ubiquitous in nature, science, and technology. Controlling crystal growth is pivotal in many industries as material properties and functions can be tailored by tuning crystal habits (e.g. size, shape, phase). In biomineralization, organisms exert excellent control over bottom-up synthesis and assembly of inorganic-organic structures (e.g. bones, teeth, exoskeletons). This is made possible by growth modifiers that range from small molecules to macromolecules, such as proteins. Molecular recognition of the mineral phase allows proteins to function as nucleation templates, matrices, and growth inhibitors or promoters. We are interested in taking a biomimetic approach to control crystallization via biomolecular growth modifiers.
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May 2017
School of Engineering
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Rensselaer Polytechnic Institute, Troy, NY
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