Preparation of biopolymer-based materials using ionic liquids for the biomedical applications
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Authors
Lee, Sang Hyun
Miyauchi, Minoru
Dordick, Jonathan S.
Linhardt, Robert J.
Issue Date
2010-04-28
Type
Book chapter
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Alternative Title
Abstract
The insolubility of unmodified biopolymers in most organic solvents has limited the applications of biopolymer-based materials and composites. Because of their inherent biocompatibility and biodegradability, such materials have many potential applications in biomedicine, including for tissue engineering, drug delivery systems, wound treatment, dialysis membranes, and biosensors. Ionic liquids (ILs) are good solvents for polar organic, nonpolar organic, inorganic and polymeric compounds. Biopolymers such as cellulose, chitin/chitosan, silk, and DNA can be fabricated from ILs into films, membranes, fibers, spheres, and molded shapes. Various biopolymer/biopolymer and biopolymer/synthetic polymer composites also can be prepared by co-dissolution of polymers into IL mixtures. Heparin/biopolymer composites are especially of interest in preparing materials with enhanced blood compatibility.
Description
ACS Symposium Series Ionic liquids application: Pharmaceutical, Therapeutics, and Biotechnology, Chapter 10, pp 115-134
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Preparation of biopolymer-based materials using ionic liquids for the biomedical applications, S. H. Lee, M. Miyauchi, J. S. Dordick, and R. J. Linhardt, ACS Symposium Series Ionic liquids application: Pharmaceutical, Therapeutics, and Biotechnology, Chapter 10, pp 115-134, 2010.
Publisher
Terms of Use
Journal
Volume
Issue
PubMed ID
DOI
ISSN
19475918
976156
976156