Cell engineering and modulation of metabolic pathways in mammalian cells for the production of glycoprotein and proteoglycan based pharmaceuticals.
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Authors
Datta, Payel
Issue Date
2013-05
Type
Electronic thesis
Thesis
Thesis
Language
ENG
Keywords
Biology
Alternative Title
Abstract
The third aim of the study involved evaluating modulation of heparan sulfate and heparin biosynthesis in recombinant CHO cells. We successfully demonstrated that sodium butyrate could be used as an additional tool besides cell engineering strategy towards production of heparin in bioengineered CHO cells.
Description
May 2013
School of Science
School of Science
Full Citation
Publisher
Rensselaer Polytechnic Institute, Troy, NY