Artificial organelles: Digital microfluidic platform for proteoglycan and glycoprotein biosynthesis

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Authors
Martin, Jeffrey G.
Beaudet, Julie M.
Dordick, Jonathan S.
Linhardt, Robert J.
Issue Date
2010-06-01
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
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Abstract
The development of artificial organelles is a new, fast-growing field in which a variety of techniques have been employed. This article gives a brief overview of the history of artificial organelles, and describes the development of an artificial endoplasmic reticulum and Golgi organelle on a digital microfluidic platform. This device should be useful in high-throughput combinatorial proteoglycan/glycoprotein synthesis, providing critical information about the control of biosynthetic pathways for these important signaling molecules.
Description
The World Scientific Journal, 10, 997-1000
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Full Citation
Artificial organelles: Digital microfluidic platform for proteoglycan and glycoprotein biosynthesis, J. G. Martin, J. M. Beaudet, J. S. Dordick, R. J. Linhardt, The World Scientific Journal, 10, 997-1000, 2010.
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1537744X
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