Sulfo-Protected Hexosamine Monosaccharides: Potentially Versatile Building Blocks for Glycosaminoglycan Synthesis

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Authors
Karst, Nathalie A.
Islam, Tasneem F.
Linhardt, Robert J.
Issue Date
2003-12-11
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
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Abstract
2,2,2-Trifluorodiazoethane was investigated as a reagent for sulfo group protection on hexosamine monosaccharides. The synthesis of glucosamine and galactosamine building blocks fully differentiated for glycosaminoglycan synthesis and the synthesis of glycosyl donors are described. The compatibility of trifluoroethylsulfonate under a variety of reaction conditions has also been investigated.
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Organic Letters, 5, 4839-4842
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Full Citation
Sulfo-Protected Hexosamine Monosaccharides: Potentially Versatile Building Blocks for Glycosaminoglycan Synthesis, N. Karst, T. F. Islam, R. J. Linhardt, Organic Letters, 5, 4839-4842, 2003.
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15237060
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