New Potent Insecticidal Agent: 4’-Fucosyl Avermectin Derivative

Authors
Wei, Guohua
Du, Yuguo
Linhardt, Robert J.
ORCID
https://orcid.org/0000-0003-2219-5833
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Other Contributors
Issue Date
2004-09-06
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Degree
Terms of Use
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Full Citation
New Potent Insecticidal Agent: 4’-Fucosyl Avermectin Derivative, G. Wei, Y. Du R.J. Linhardt, Tetrahedron Letters, 45, 6895-6898, 2004.
Abstract
A 4′-fucosyl avermectin derivative was designed and synthesized. This new avermectin derivative showed excellent in vivo bioactivity against cabbage larvae when compared to commercially available avermectin B1a. In this synthesis, thioglycosyl donors, but not trichloroacetimidates, were found compatible with sugar-macrolide synthesis under rt promotion with NIS or I2 in N-methylpyrrolidone.
Description
Tetrahedron Letters, 45, 6895-6898
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Department
The Linhardt Research Labs.
The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
Publisher
Relationships
The Linhardt Research Labs Online Collection
Rensselaer Polytechnic Institute, Troy, NY
Tetrahedron Letters
https://harc.rpi.edu/
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https://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.tetlet.2004.07.092