Green glycosylation using ionic liquid to prepare alkyl glycosides for studying carbohydrate-protein interactions by SPR
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Authors
Muñoz, F.J.
Pérez, J.
André, S.
Gabius, H.J.
Sinisterra, J.V.
Hernáiz, M.J.
Linhardt, Robert J.
Issue Date
2009-03-09
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Alternative Title
Abstract
Several simple glycosides of D-glucose (Glc) and N-acetyl-D-galactosamine (GalNAc) were prepared in a single step glycosylation reaction using unprotected and unactivated sugar donors. The resulting GalNAc glycoside, containing a bifunctional linker, was used to immobilize this glycoconjugate to a self assembled monolayer on a gold biosensor chip. Surface plasmon resonance (SPR) experiments demonstrated that this immobilized glycoconjugate bound to GalNAc specific lectin, Viscum album agglutinin.
Description
Green Chemistry, 11, 373-379
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Green glycosylation using ionic liquid to prepare alkyl glycosides for studying carbohydrate-protein interactions by SPR, F. J. Muñoz, J. Pérez, S. André, H.-J. Gabius, J. V. Sinisterra, M. J. Hernáiz, and R. J. Linhardt, Green Chemistry, 11, 373-379, 2009.
Publisher
Terms of Use
Journal
Volume
Issue
PubMed ID
DOI
ISSN
14639270
14639262
14639262