[[The]] characterization of bone extracellular matrix quality by proteome profiling, focusing on osteocalcin and glycation
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Authors
Thomas, Corinne J.
Issue Date
2017-05
Type
Electronic thesis
Thesis
Thesis
Language
ENG
Keywords
Biomedical engineering
Alternative Title
Abstract
This study shows the development and execution of protocols that allow for a comparison of the proteome of healthy bone to fragile bone, and identifies specific post-translational modifications and/or the nature of such modifications in both collagenous (Type I collagen) and non-collagenous (osteocalcin) proteins associated with aging, altered microbiome and increased bone fragility.
Description
May 2017
School of Engineering
School of Engineering
Full Citation
Publisher
Rensselaer Polytechnic Institute, Troy, NY