[[The]] characterization of bone extracellular matrix quality by proteome profiling, focusing on osteocalcin and glycation

Authors
Thomas, Corinne J.
ORCID
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Other Contributors
Vashishth, Deepak
Dordick, Jonathan
Karande, Pankaj
Ledet, Eric H.
Issue Date
2017-05
Keywords
Biomedical engineering
Degree
PhD
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
Abstract
This study shows the development and execution of protocols that allow for a comparison of the proteome of healthy bone to fragile bone, and identifies specific post-translational modifications and/or the nature of such modifications in both collagenous (Type I collagen) and non-collagenous (osteocalcin) proteins associated with aging, altered microbiome and increased bone fragility.
Description
May 2017
School of Engineering
Department
Dept. of Biomedical Engineering
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
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