Nano-based Neoproteoglycans – Blood Compatible Carbon Nanotubes

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Authors
Murugesan, Saravanababu
Park, Tae Joon
Yang, Hoichang
Mousa, Shaker
Linhardt, Robert J.
Issue Date
2006-04-11
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
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Abstract
Although nanotechnology has provided a rich variety of nanomaterials (1–100 nm) for in vivo medical applications, the blood compatibility of all these nanobiomaterials is still largely unexamined. Here, we report the preparation of blood-compatible carbon nanotubes (CNTs) that potentially represent the building blocks for nanodevices having in vivo applications. Activated partial thromboplastin time (APTT) and thromboelastography (TEG) studies prove that heparinization can significantly enhance the blood compatibility of nanomaterials.
Description
Langmuir, 22,3461-3463
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Nano-based Neoproteoglycans – Blood Compatible Carbon Nanotubes, S. Murugesan, T. Park, H. Yang, S. Mousa and R. J. Linhardt, Langmuir, 22,3461-3463, 2006.
Publisher
American Chemical Society (ACS)
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ISSN
7437463
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