Heparin as a Potential Therapeutic Agent to Reverse Vascular Remodeling
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https://orcid.org/0000-0003-2219-5833
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Book chapter
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ENG
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Abstract
Vascular changes after chronic hypoxia are characterized by hyperplasia, hypertrophy, and migration of smooth muscle cells (SMCs) in the media of muscular and partially muscular pulmonary arteries (1,2). A number of factors are known to cause SMC migration, such as serum, platelet-derived growth factor (PDGF)- BB (3,4), transforming growth factor-β (5), fibrinogen (6), oxidized low-density lipoprotein (7,8), and angiotensin II (9,10).
Description
Proteoglycans and Lung Disease, H.G. Garg, P.J. Roughley, C.A. Hales (Eds.), Chapter 18, 377-398
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Heparin as a Potential Therapeutic Agent to Reverse Vascular Remodeling, H. Garg, B.T. Thompson, R.J. Linhardt, C.A. Hales, Proteoglycans and Lung Disease, H.G. Garg, P.J. Roughley, C.A. Hales (Eds.), Chapter 18, 377-398, 2003.