The role of electrotonic junctions between pyramidal cells in the cortex
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Authors
Crodelle, Jennifer A.
Issue Date
2017-08
Type
Electronic thesis
Thesis
Thesis
Language
ENG
Keywords
Mathematics
Alternative Title
Abstract
In this study, we closely follow experimental data to construct a detailed, comprehensive model with both synaptic and electric coupling for both excitatory and inhibitory neurons using a modified version of the Hodgkin-Huxley equations. We organize the neurons on a grid to capture the highly structured spatial properties of a network containing both synaptic and electric connections, and to ensure that the probability of neurons being coupled is dependent on their location within the network. We use this model to examine the dynamical regimes that emerge through the incorporation of strong, electrotonic junctions between pairs of pyramidal cells, with a specific interest in the emergence and properties of synchrony.
Description
August 2017
School of Science
School of Science
Full Citation
Publisher
Rensselaer Polytechnic Institute, Troy, NY