The role of electrotonic junctions between pyramidal cells in the cortex

Authors
Crodelle, Jennifer A.
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Other Contributors
Kovacic, Gregor
Kramer, Peter Roland, 1971-
Banks, Jeffrey
Cai, David
Issue Date
2017-08
Keywords
Mathematics
Degree
PhD
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
Abstract
In this study, we closely follow experimental data to construct a detailed, comprehensive model with both synaptic and electric coupling for both excitatory and inhibitory neurons using a modified version of the Hodgkin-Huxley equations. We organize the neurons on a grid to capture the highly structured spatial properties of a network containing both synaptic and electric connections, and to ensure that the probability of neurons being coupled is dependent on their location within the network. We use this model to examine the dynamical regimes that emerge through the incorporation of strong, electrotonic junctions between pairs of pyramidal cells, with a specific interest in the emergence and properties of synchrony.
Description
August 2017
School of Science
Department
Dept. of Mathematical Sciences
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
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