Troponin C isoforms influence stretch activation and mechanical properties of Drosophila muscles
Loading...
Authors
Eldred, Catherine
Issue Date
2014-08
Type
Electronic thesis
Thesis
Thesis
Language
ENG
Keywords
Biochemistry and biophysics
Alternative Title
Abstract
Flying insects have developed means to optimize their power output in their flight muscles to enable the smallest possible set of muscles to reliably lift the body mass of the insect and maneuver in flight. Some of these adaptations phenotypically correspond to biochemical adaptations evolved by vertebrate hearts to beat efficiently when rest or failure is not possible. One of those adaptations is stretch activation, which has been suggested to be physiologically relevant in the progression of heart disease. Homologies exist between the two systems, which make insect flight muscles a good fit for heart disease research.
Description
August 2014
School of Science
School of Science
Full Citation
Publisher
Rensselaer Polytechnic Institute, Troy, NY