[[The]] role of extra-cellular matrix proteins and post-translational modifications on bone fracture

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Authors
Bailey, Stacyann Morgan
Issue Date
2016-12
Type
Electronic thesis
Thesis
Language
ENG
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Biomedical engineering
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Abstract
Finally, the contribution of PTMs to bone fracture in a type-II diabetic model was evaluated. Obesity-induced diabetes resulted in an increase in the amount of non-enzymatic cross-links and an associated reduction in bone propagation toughness. This project provides an understanding of the role of bone matrix proteins and their modifications on bone size, shape, strength, and fracture.
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December 2016
School of Engineering
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Rensselaer Polytechnic Institute, Troy, NY
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