Recent Advances in the Synthesis of C-oligosaccharides

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Authors
Yuan, Xuejun
Linhardt, Robert J.
Issue Date
2005-12-01
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Research Projects
Organizational Units
Journal Issue
Alternative Title
Abstract
This paper reviews the recent advances in the synthesis of catabolically stable sugar mimetics, C-oligosaccharides. These compounds are synthetic analogs of the naturally occurring O-oligosaccharides, in which the interglycosidic oxygen has been replaced by a methylene group. This review is organized in terms of chemistry used to assemble C-oligosaccarides under the sub-headings: anionic approaches, cationic methods, reductive glycosyl samarium chemistry, cyclization methodology, and free radical chemistry.
Description
Current Topics in Medicinal Chemistry, 5, 1393-430
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Full Citation
Recent Advances in the Synthesis of C-oligosaccharides, X. Yuan, R. J. Linhardt, Current Topics in Medicinal Chemistry, 5, 1393-430, 2005.
Publisher
Bentham Science
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Journal
Volume
Issue
PubMed ID
DOI
ISSN
15680266
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