Bioerodable Polyanhydrides for Controlled Drug Delivery

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Authors
Linhardt, Robert J.
Rosen, H.B.
Langer, R.
Issue Date
1983
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Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
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Abstract
Initial in vitro and in vivo (rat) studies using a poly(anhydride), poly[bis(p-carboxyphenoxy)methane], as a bioerodible matrix for controlled drug delivery are described. Drug delivery matrices fabricated from this material and containing cholic acid showed a period of nearly zero-order erosion kinetics during which this steroid was released at nearly the same constant rate.
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Polymer Preprints, 24, 47-48
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Bioerodable Polyanhydrides for Controlled Drug Delivery, R.J. Linhardt, H.B. Rosen, R. Langer, Polymer Preprints, 24, 47-48 (1983).
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