Stochastic hydrodynamics of colonial microswimmers

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Authors
Ashenafi, Yonatan
Issue Date
2021-05
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Electronic thesis
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en_US
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Mathematics
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Abstract
Functions of microorganisms like looking for nutrition and biological processes such as infectionand reproduction are only possible due to micro-fluidic motion. Developments over the past two decades in tracking and manipulation at the micro-fluidic level have made possible accurate measurements of micro-hydrodynamical flows and have provided access to a wealth of interesting biological and synthetic phenomena and a means to test the phenomena's corresponding theories. This thesis focuses on these corresponding theories of micro-hydrodynamical phenomena.Our aim is to answer questions of individual and collective mobility for colonial microswimmers and micro-rotors and of the fluid flows they generate. We wish to give analytical expression to the individual aggregated swimmers' mobility statistics, and the environmental interaction of these swimmers both with each other and with reactive proles such as attractant chemicals. Our work is effectively split into three projects. The first research project focuses onthe statistical mobility properties of colonial microswimmers typified by an animal-like group of protozoa called Choanoflagellates. The second research project focuses on the function of multicellularity for the taxis and kinesis effectiveness of protozoa. Finally, the third research project focuses on the stability and correlations of suspensions of micro-swimmers and microrotors. In our investigations we applied fluid mechanical principles for the flow modeling and insights from biophysical experiments for the swimmer modeling. We used asymptotic and multi-scale methods for coarse graining the physical models and we compared the results from these asymptotic derivations with Monte Carlo simulations and matrix-based computations of the full models.
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May2021
School of Science
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Rensselaer Polytechnic Institute, Troy, NY
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