Previews: Heparin-Induced Cancer Cell Death
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Authors
Linhardt, Robert J.
Issue Date
2004
Type
Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Alternative Title
Abstract
Heparin uptake into cancer cells can be promoted by conjugation to poly (β-amino ester)s. Internalized heparin is cytotoxic, causing cancer cell death by interfering with transcription factor activity and inducing apoptosis, but only certain poly(β-amino ester)s promote this activity.
Description
Chemistry & Biology, 11, 420-422
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Previews: Heparin-Induced Cancer Cell Death, R. J. Linhardt, Chemistry & Biology, 11, 420-422, 2004.