Previews: Heparin-Induced Cancer Cell Death

Authors
Linhardt, Robert J.
ORCID
https://orcid.org/0000-0003-2219-5833
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Other Contributors
Issue Date
2004
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
Degree
Terms of Use
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Full Citation
Previews: Heparin-Induced Cancer Cell Death, R. J. Linhardt, Chemistry & Biology, 11, 420-422, 2004.
Abstract
Heparin uptake into cancer cells can be promoted by conjugation to poly (β-amino ester)s. Internalized heparin is cytotoxic, causing cancer cell death by interfering with transcription factor activity and inducing apoptosis, but only certain poly(β-amino ester)s promote this activity.
Description
Chemistry & Biology, 11, 420-422
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Department
The Linhardt Research Labs.
The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
Publisher
Relationships
The Linhardt Research Labs Online Collection
Rensselaer Polytechnic Institute, Troy, NY
https://harc.rpi.edu/
Access
https://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.chembiol.2004.04.001