[[The]] role of cortical and cancellous bone quality on vertebral fragilty

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Authors
Bradke, Brian Scott
Issue Date
2014-05
Type
Electronic thesis
Thesis
Language
ENG
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Biomedical engineering
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Abstract
Therefore, the objective of this doctoral research is to combine biochemical, mechanical, and computational methods to: a) better characterize the load sharing role of cortical and cancellous bone within the vertebrae, b) determine the effect of AGE accumulation on load sharing within the vertebrae, and c) validate the feasibility of reversing the effects of NEG-mediated AGE crosslinking using n-Phenacylthiazolium Bromide.
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May 2014
School of Engineering
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Rensselaer Polytechnic Institute, Troy, NY
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