Facile Synthesis of (±)-Paeonilide
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ORCID
https://orcid.org/0000-0003-2219-5833
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Article
Language
ENG
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Abstract
(+/-)-Paeonilide, a novel monoterpenoid metabolite from the roots of Paeonia delavayi showing anti-platelet activating factor activity, is convergently synthesized in five steps with 59% overall yield. The application of benzoyl peroxide-promoted radical addition of unsaturated ester to aldehyde and subsequent topologically favored cyclization greatly simplified the synthesis.
Description
Journal of Organic Chemistry, 72, 3952-3954
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Full Citation
Facile Synthesis of (±)-Paeonilide, Y. Du, J Liu, R. J. Linhardt, Journal of Organic Chemistry, 72, 3952-3954, 2007.
Publisher
American Chemical Society (ACS)