Inteins as biomolecular switches : applications in drug discovery, protein purification, and stress response

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Authors
Pearson, C. Seth
Issue Date
2018-05
Type
Electronic thesis
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Language
ENG
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Chemical engineering
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Abstract
Inteins are protein elements that autocatalytically excise themselves from a host protein in a process called protein splicing. The two flanking sequences of the host protein, called the N- and C-exteins, are subsequently ligated with a native peptide bond, resulting in a mature protein.
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May 2018
School of Engineering
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Rensselaer Polytechnic Institute, Troy, NY
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