Optical tomography and light irradiation to reduce bacterial loads in oral health application

Authors
Long, Feixiao
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Other Contributors
Intes, Xavier
Kotha, Shiva
Wang, Ge, 1957-
Li, Fengyan
Hahn, Juergen
Issue Date
2016-05
Keywords
Biomedical engineering
Degree
PhD
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
Abstract
Light based modalities can enable detection of physiologic functional parameters and can be used as therapies, especially in structures close to the surface, such as teeth. The integrity of teeth is dependent on the physiological function of its biological component: cells in the pulp cavity. Previous studies suggest that impairment of the biological component, as occurs in the presence of cavities (due to bacterial biofilms) or when the tooth structure has been compromised by other means (such as cracks), affects some measures of physiology (e.g. oxygenation). Because it may be possible to detect impairment of pulp function through changes in its oxygenation, and since currently used pulse oximetry based methods provide measures that are affected by other variables, we evaluate whether it is possible to provide 3-D measurements of pulp activity. When the tooth decay forms and surgery has to be performed to prevent further damage of teeth, it is necessary to determine whether the dental fillings provide good coverage of the surgical cavity. It is noted that teeth structures exhibit extremely high absorption and scattering coefficients relative to other tissues on which optical methods have conventionally been used (e.g. wounds, breast and brain). So it is important to determine whether optical methods are sensitive enough to enable imaging through teeth to obtain 3-D measurements of pulp or dental fillings.
Description
May 2016
School of Engineering
Department
Dept. of Biomedical Engineering
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
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