Multiscale and multi-domain feature analysis of salivary gland morphogenesis

Authors
Baskaran, Abhirami
ORCID
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Other Contributors
Yener, Bülent, 1959-
Stewart, Charles V.
Zaki, Mohammed J., 1971-
Issue Date
2013-12
Keywords
Computer science
Degree
MS
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
Abstract
Branching morphogenesis is an important developmental mechanism in glands such as salivary glands, lungs, kidney and mammary glands [2]. Future breakthroughs such as building artificial glands to replace dysfunctional and diseased glands require a profound understanding of branching morphogenesis. Development of computer-aided techniques that can model branching patterns will provide a clear insight into the underlying mechanisms. Mouse submandibular salivary gland (SMG) provides good ground for the study of branching morphogenesis since it is easy to culture and exhibits well defined branching patterns. SMG exhibits boundary changes called clefts that begin as small indentations in the surface of the gland. These structures progress towards the interior of the gland finally forming branches.
Description
December 2013
School of Science
Department
Dept. of Computer Science
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
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