Multiscale and multi-domain feature analysis of salivary gland morphogenesis
Loading...
Authors
Baskaran, Abhirami
Issue Date
2013-12
Type
Electronic thesis
Thesis
Thesis
Language
ENG
Keywords
Computer science
Alternative Title
Abstract
Branching morphogenesis is an important developmental mechanism in glands such as salivary glands, lungs, kidney and mammary glands [2]. Future breakthroughs such as building artificial glands to replace dysfunctional and diseased glands require a profound understanding of branching morphogenesis. Development of computer-aided techniques that can model branching patterns will provide a clear insight into the underlying mechanisms. Mouse submandibular salivary gland (SMG) provides good ground for the study of branching morphogenesis since it is easy to culture and exhibits well defined branching patterns. SMG exhibits boundary changes called clefts that begin as small indentations in the surface of the gland. These structures progress towards the interior of the gland finally forming branches.
Description
December 2013
School of Science
School of Science
Full Citation
Publisher
Rensselaer Polytechnic Institute, Troy, NY