Synthesis of the Bis-Tetrahydropyrano[2,3-b:2’,3’-e] Piperazine Ring System: A New Tricyclic Heterocycle from D-Glucosamine

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Authors
Kerns, Robert J.
Toida, Toshihiko
Linhardt, Robert J.
Issue Date
1996-01-01
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Article
Language
ENG
Keywords
Biology , Chemistry and chemical biology , Chemical and biological engineering , Biomedical engineering
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Abstract
2-Amino-3,4,6-tri-O-benzyl-2-deoxy-D-glucopyranose was transformed into its bis(tetrahydropyranyl)piperazine dimer (4) by reaction with 1,1′-thionyldiimidazole or 1,1′-sulfonyldiimidazole. This dimeric form of glucosamine is the first representative of this previously unknown heterocyclic ring system.
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Journal of Carbohydrate Chemistry, 15, 581-590
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Full Citation
Synthesis of the Bis-Tetrahydropyrano[2,3-b:2’,3’-e] Piperazine Ring System: A New Tricyclic Heterocycle from D-Glucosamine, R.J. Kerns, T. E. Toida, R.J. Linhardt, Journal of Carbohydrate Chemistry, 15, 581-590, 1996.
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7328303
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